NAD+ (500mg)
$139.99
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells, central to redox reactions and metabolic regulation. In research settings, NAD+ is investigated for its role in mitochondrial bioenergetics, sirtuin deacetylase activation, DNA repair pathway signaling, and cellular aging models.
BioRhex supplies NAD+ as a research compound manufactured in a GMP-compliant US facility, tested to ≥99% purity via HPLC and mass spectrometry, and supplied strictly for controlled laboratory research — not for human or animal use.
- In stock
- COA-verified
- ≥99% purity.
- USA manufactured.
- In stock
- COA-verified
- ≥99% purity.
- USA manufactured.
- COA-verified
- In stock
- ≥99% purity.
- USA manufactured.
What Is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells, central to redox reactions and metabolic regulation.
In research settings, NAD+ is investigated for its role in mitochondrial bioenergetics, sirtuin deacetylase activation
Compound Overview
NAD+ is a dinucleotide coenzyme extensively studied in cellular biology. In vitro and preclinical research models examine how NAD+ availability and modulation may influence:
• Mitochondrial respiratory chain activity and ATP synthesis modeling
• Sirtuin (SIRT1–SIRT7) deacetylase pathway activation in aging models
• PARP-mediated DNA repair mechanism research
• CD38 enzyme activity and NAD+ consumption dynamics
• NAD+/NADH ratio effects on glycolytic and oxidative phosphorylation pathways
All findings referenced are from controlled research environments and do not represent clinical outcomes or therapeutic claims.
History of NAD+
NAD+ was first characterized by Arthur Harden and William John Young in the early 20th century during fermentation research. Its central role in cellular redox biology was established through subsequent decades of biochemical investigation.
Research interest in NAD+ as a metabolic and longevity-associated molecule intensified following findings linking NAD+ depletion with mitochondrial dysfunction and aging-related pathway dysregulation in preclinical models. The discovery of NAD+-dependent sirtuins further expanded research into its role as a regulatory coenzyme in gene expression and stress response pathways.
NAD+ remains one of the most actively investigated molecules in cellular metabolism, aging biology, and bioenergetics research, studied exclusively within laboratory and non-clinical settings.
Molecular Structure
Adenosine-5′-diphosphoribose + Nicotinamide — dinucleotide coenzyme (not a single peptide chain)
Research Findings
Published and preclinical research on NAD+ covers several areas of scientific investigation, including:
Mitochondrial function modeling: Studies examine NAD+ levels in relation to electron transport chain efficiency and ATP production dynamics in cellular models.
Sirtuin pathway research: Research explores how NAD+ availability modulates SIRT1 and related deacetylase signaling in metabolic and aging pathway models.
DNA repair signaling: Laboratory findings evaluate NAD+’s role in PARP enzyme activation and double-strand break repair responses.
Cellular senescence models: Preclinical studies examine correlations between NAD+ depletion and senescence-associated pathway markers.
Metabolic pathway interactions: Research investigates NAD+/NADH ratios and their downstream effects on cellular energy metabolism dynamics.
All findings referenced are from controlled, non-clinical research models and do not imply therapeutic or clinical application.
References
FAQ
What type of research is NAD+ used for?
What type of research is NAD+ used for?
NAD+ is used in laboratory research settings. All supplied compounds are intended strictly for in vitro and preclinical research purposes. Use is limited to controlled scientific environments.
Where is BioRhex’s NAD+ manufactured?
Where is BioRhex’s NAD+ manufactured?
All BioRhex compounds, including NAD+, are manufactured in a GMP-compliant facility located in the United States.
What testing does BioRhex conduct on NAD+?
What testing does BioRhex conduct on NAD+?
Every batch of NAD+ undergoes third-party HPLC purity testing, mass spectrometry identity verification, and sterility testing. A Certificate of Analysis is included with every order, documenting batch-specific purity data at a ≥99% threshold.
Is NAD+ approved for human use?
Is NAD+ approved for human use?
No. NAD+ is not FDA-approved and is not intended for human or animal administration. It is supplied exclusively for laboratory research purposes.
Who should handle this compound?
Who should handle this compound?
Only qualified personnel in controlled laboratory settings following appropriate safety and handling protocols.
Research Use Only
All BioRhex compounds are supplied strictly for laboratory research purposes. Not for human or animal consumption, medical use, or therapeutic application. NAD+ is not FDA-approved for any medical purpose. Nothing on this page should be interpreted as health guidance or applied outside controlled research settings.
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