DSIP

Name: DSIP
SKU: 1140
Availability: InStock

$49.00

Size

Clear

In stock
COA-verified
≥99% purity.
USA manufactured.
In stock
COA-verified
≥99% purity.
USA manufactured.
COA-verified
In stock
≥99% purity.
USA manufactured.
In stock
≥99% purity.
USA manufactured.
In stock
≥99% purity.
USA manufactured.
In stock
≥99% purity.
USA manufactured.

WHAT IS DSIP?

DSIP (Delta Sleep-Inducing Peptide) is a nine-amino-acid neuropeptide first isolated in 1974 from the cerebral venous blood of rabbits during states of induced sleep. In research settings, DSIP is investigated for its interactions with delta-wave electrophysiological activity, circadian regulation, and neuromodulatory pathway models.
BioRhex supplies DSIP as a research compound manufactured in a GMP-compliant US facility, tested to ≥ 99% purity via HPLC and mass spectrometry, and supplied strictly for controlled laboratory research — not for human or animal use.

DSIP is a nonapeptide investigated for its interactions with sleep-regulatory and neuroendocrine signaling systems. In vitro and preclinical models examine how DSIP may influence:

Delta-wave (slow-wave) electrophysiological activity in neural models
Circadian and locomotor rhythm regulation
Neuroendocrine and hormonal signaling interactions
Stress-response and corticosteroid-associated pathways
NMDA and GABA receptor-associated neuromodulation

DSIP was first isolated in 1974 by Swiss researchers Monnier and Schoenenberger, who identified a peptide fraction from the cerebral blood of rabbits associated with delta-sleep electroencephalographic patterns.
In vitro and preclinical findings related to DSIP’s interactions with sleep architecture and neuroendocrine regulation expanded its use as a research tool in chronobiology and neuropeptide signaling studies.
DSIP continues to be investigated within sleep-regulatory and neuromodulatory pathway research in controlled laboratory environments.

Reserch-grade coenzyme compound visualization.

COMPOUND

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

TYPE

Nonapeptide (neuropeptide)

MOLECULAR FORMULA

C35H48N10O15

MOLECULAR WEIGHT

848.81 g/mol

PURITY

≥99%

ANALYSIS

HPLC Verified

STORAGE

Store at -20°C. Protect from light and moisture.

CLASSIFICATION

Reserch Use Only

Research Findings

Published and preclinical research on DSIP covers several areas of scientific investigation, including:

Sleep regulation research: Studies examine DSIP’s interactions with delta-wave activity and sleep-onset dynamics in preclinical models.
Chronobiology research: Studies examine DSIP’s effects on circadian and locomotor rhythms in experimental systems.
Neuroendocrine research: Studies examine DSIP’s interactions with hormonal and corticosteroid-associated signaling.
Neuroprotection research: Studies examine DSIP’s associations with oxidative-stress and neuronal-protection markers in preclinical models.

All findings referenced are from controlled, non-clinical research models and do not imply therapeutic or clinical application.

References

1. Graf MV, Kastin AJ (1984). Delta-sleep-inducing peptide (DSIP): a review. Neuroscience & Biobehavioral Reviews, 8(1), 83–93. https://doi.org/10.1016/0149-7634(84)90022-8

2. Yehuda S, Kastin AJ, Coy DH (1980). Thermoregulatory and locomotor effects of DSIP: paradoxical interaction with d-amphetamine. Pharmacology Biochemistry and Behavior, 13(6), 895–900. https://doi.org/10.1016/0091-3057(80)90225-7

3. Schneider-Helmert D, Schoenenberger GA (1981). The influence of synthetic DSIP on disturbed human sleep. Experientia, 37(9), 913–917. https://doi.org/10.1007/BF01971753

4. Backmund M, Meyer K, Rothenhaeusler HB, Soyka M (1998). Opioid detoxification with delta sleep-inducing peptide. Journal of Clinical Psychopharmacology, 18(3), 246–247. https://doi.org/10.1097/00004714-199806000-00016

FAQ

What type of research is DSIP used for?

DSIP is used in laboratory research settings. All supplied compounds are intended strictly for in vitro and preclinical research purposes. Use is limited to controlled scientific environments.

Where is BioRhex’s DSIP manufactured?

All BioRhex compounds, including DSIP, are manufactured in a GMP-compliant facility located in the United States.

What testing does BioRhex conduct on DSIP?

Every batch of DSIP undergoes third-party HPLC purity testing, mass spectrometry identity verification, and sterility testing. A Certificate of Analysis is included with every order, documenting batch-specific purity data at a ≥ 99% threshold.

Is DSIP approved for human use?

No. DSIP is not FDA-approved and is not intended for human or animal administration. It is supplied exclusively for laboratory research purposes.

Who should handle this compound?

Only qualified personnel in controlled laboratory settings following appropriate safety and handling protocols.

All BioRhex compounds are supplied strictly for laboratory research purposes. Not for human or animal consumption, medical use, or therapeutic application. DSIP is not FDA-approved for any medical purpose. Nothing on this page should be interpreted as health guidance or applied outside controlled research settings.